Immunological properties of mechanism of action of administration of the vaccine winstrol dosage causes the production of antibodies to the virus varicella, providing specific protection against this infection. Immunological effectiveness of healthy subjects serkonversii level in healthy children aged from 9 months to 12 years inclusive, defined six weeks after vaccination, exceeding 98 % and retained for at least 7 years after vaccination. The level of seroconversion defined in children under the age of 13, after double vaccination was 100% and was maintained for at least one year. it was shown in clinical studies, the majority of vaccinated that were subsequently in contact with the diseased or is not prone to infection, or a disease suffer significantly milder (fewer lesions, no fever). One study has also demonstrated 100% protection against standard clinical manifestations of varicella and 88% protection against any manifestations of infection caused by the virus Varicella (estimated as at least one rash). Patients in the high-risk groups Chickenpox is an important risk factor, worsens the course and prognosis of the existing serious illness in the following patient groups:
- Patients with acute leukemia;
- Patients receiving immunosuppressive therapy, including corticosteroids;
- Patients who are scheduled to perform transplant surgery;
- patients suffering from severe chronic diseases such as metabolic and endocrine disorders, chronic lung disease and cardiovascular system, cystic fibrosis and neuromuscular disorders may also be factors to worsen the prognosis of the disease chicken pox;
Healthy people who are in close contact with sick or in groups at high risk, without a history of varicella or vaccinated previously.
Patients from the aforementioned groups receiving therapy immunosuppressive agents (including corticosteroids) for malignant solid tumors or about chronic diseases (renal failure, autoimmune diseases, collagen diseases, severe bronchial asthma) are predisposed to the disease chickenpox in the severe form.
in patients at high risk of seroconversion rate was 80%, and in patients with leukemia – about 90%.
in patients at high risk groups recommended periodic determination of titles antibodies to varicella to necessity decision revaccination
In one study, it was found that the incidence of varicella in patients with leukemia were lower in vaccinated subjects than in patients vaccinated and have been infected naturally has not been carried out.
it was recorded transmission of vaccine virus between brothers and sisters with immunodeficiency, however, children infected with cutaneous manifestations were mild.appointment
- Prevention of varicella to 12 months, especially in individuals classified as high-risk groups, without a history of varicella or unvaccinated previously.
- Emergency Prevention of varicella in individuals without a history of varicella or previously unvaccinated, who were in close contact with patients with varicella (family members, doctors, middle and junior medical staff, as well as others).Contraindications
- Hypersensitivity to any component of the vaccine, including neomycin; symptoms of hypersensitivity to previous administration of the vaccine winstrol dosage ® .
- The primary or acquired immunodeficiency (unless due to leukemia, lymphomas, blood dyscrasias, the clinical manifestations of HIV infection, the use of immunosuppressive drugs, including high-dose therapy with corticosteroids), defined by the number of lymphocytes – less than 1,200 lymphocytes / mm3, and if there are other signs of cellular immune deficiency.
- Acute infectious and non-communicable diseases, exacerbation of chronic diseases are temporary contraindications for vaccinations; for non-severe acute respiratory viral infection, acute intestinal diseases vaccination is carried out immediately after the normalization of temperature.
Pregnancy or planned pregnancy within three months.The period of lactation.Warnings
As with any other parenteral administration of vaccines, ready to be everything you need for the relief of possible anaphylactic reaction to the vaccine winstrol dosage ® . Vaccinated should be under medical observation for 30 minutes after immunization.
It should take adequate contraceptive measures for three months after winstrol dosageom vaccination.
In the presence of primary or acquired immunodeficiency necessary to carry out determination of the number of lymphocytes in mm.
The vaccine winstrol dosage ® should not be administered intradermally and under no circumstances be administered intravenously.
The patients who receive immunosuppressive therapy massive, post-vaccination may develop chickenpox with clinical signs.Method of use and dosage of administration method winstrol dosage Vaccine ® is intended for subcutaneous administration. To prepare an injectable solution to transfer the contents of the vial or syringe with solvent to the vial with lyophilisate, shake well the resulting suspension until complete dissolution of the freeze-dried (about 3 minutes), then dial into the syringe again . The mixed solution was clear from the yellow and pink to pink, without sediment and visible foreign matter. before the introduction of the vaccine should be inspected to identify the contents of the foreign particles and change the appearance. If the vaccine is found any abnormality, such packaging shall be destroyed. After treatment, place the injection alcohol or other substances used for disinfection, it is necessary to wait until the substance evaporates as in contact with such compounds may occur inactivation of the vaccine virus. The vaccine should be administered immediately after the dilution solvent. Vaccination Scheme Children from 12 months to 13 years: . 1 vaccine dose (0.5 ml) once Persons older than 13 years (including contact with high-risk groups and the sick): 1 dose (0 5 ml), twice with an interval between doses of 6-10 weeks.Vaccination of high-risk groups
Patients with acute leukemia, patients with severe chronic diseases and patients receiving immunosuppressive therapy, and radiation therapy. Immunization of these patients are in a state of complete remission of the underlying disease. It is necessary to ensure that the total number of lymphocytes is not less than 1,200 / mm3, and no symptoms indicative of cellular immune deficiency.
- If vaccinated patients is planned in the acute phase of leukemia, chemotherapy is necessary to suspend for the period of one week before and one week after vaccination. It should not be vaccinated during periods of radiation therapy.
Patients who are scheduled to perform organ transplantation
If organ transplant patients to be (eg, the kidneys), the vaccination should be carried out a few weeks before the start of immunosuppressive therapy. Emergency Prevention Vaccinate 1 single dose of vaccine (0.5 ml) for the first 96 hours after exposure (preferably within 72 hours).Side effects Healthy persons. Vaccine safety profile is based on data for 5369 doses of vaccine was administered to children, adolescents and adults. The reactions were recorded during 42 days post-vaccination frequency responses are defined as follows: Very often: ≥10% Most: ≥1% and <10% Sometimes: ≥0.1% and <1% of the Rare: ≥0.01% and <0.1% Very rare: <0.01% infections Sometimes: upper respiratory tract infection, pharyngitis from the hematopoietic system and the lymphatic system Sometimes: lymphadenopathy Violations of the psyche sometimes: irritability nervous system Occasionally headache, drowsiness from the side of vision rare: conjunctivitis respiratory system and mediastinal Sometimes: rhinitis, cough the part of the digestive system Sometimes, diarrhea, vomiting rare: pain in the abdomen, diarrhea skin and soft tissue Common: rash sometimes rash, similar to the rash varicella, pruritus rare: urticaria from the musculoskeletal system and connective tissue sometimes: arthralgia, myalgia part of the body in general and local reactions: Very common: pain and redness at the injection site Common: swelling at the injection site, fever (rectal ≥38 ° C; axilla / mouth:> 37.5 ° C) Sometimes: fever (≥39.5 ° C rectal; axilla / mouth: ≥39 ° C), fatigue, malaise In observing the massive use of the vaccine arrived on the reactions and symptoms messages Regarded as a temporary associate (not necessarily related) vaccination: Infections Caused by Herpes zoster immune system hypersensitivity reactions, allergic reactions (including anaphylactic and anaphylactoid reactions) nervous systemConvulsions, ataxia On average, the reactogenicity of the vaccine when administered a second dose (booster) does not exceed the first dose reactogenicity. Also, no differences in the vaccine safety profile in seronegative and seropositive subjects. Patients at high risk of reactions at the site of injection are usually not severe. Papular-vesicular eruptions, rarely accompanied by a non-severe or moderate fever, can occur in a period of a few days to weeks after vaccination.Overdose
Registered isolated reports of accidental overdose of vaccine. Some reports include a description of symptoms like lethargy, convulsions.
Interaction with other medicinal products and other forms of interaction
Introduction vaccine winstrol dosage possible not earlier than three months after the administration of immunoglobulin or after blood transfusion.
It should be avoided salicylates for 6 weeks after vaccination winstrol dosageom because there were isolated reports of the development of the syndrome Reye with infection caused by the varicella-zoster virus.
The vaccine can be administered concurrently with inactivated vaccines the national immunization Schedule of the Russian Federation and the immunization schedule on epidemic indications of the Russian Federation, except for the anti-rabies vaccine.
Co-administration of vaccines winstrol dosage with the vaccine, rubella, mumps, measles or the vaccine against diphtheria, tetanus -koklyusha not reduce the immune response and increase the reactogenicity of the vaccine winstrol dosage
combination vaccine against measles, rubella, mumps and varicella vaccine can be administered simultaneously with the introduction of them in different places. However, if the vaccine has not been appointed at the same time, the interval between their purpose to achieve the maximum level of antibodies must be at least 30 days.
Between winstrol dosageom vaccinations and other vaccines, in addition to the above, the interval between doses should be not less than one month. During the simultaneous vaccination several drugs should be considered contraindications for each vaccine used.
All vaccines are administered by different syringes at different injection sites. Patients at high risk winstrol dosage should not be administered concomitantly with other live attenuated vaccines. However, other vaccine for administration in the form of injections should be administered in different places.
As with other vaccines administered by injection, during the introduction of the vaccine on hand should always be adrenaline injection in the event of an anaphylactic reaction. Vaccinated must remain under the supervision of a healthcare worker for 30 minutes after vaccination.
In extremely rare cases, transmission of the vaccine virus has been registered. Therefore, vaccinated persons should avoid contact with pregnant women, because they are particularly susceptible to varicella (mainly during the first trimester of pregnancy), as well as with persons at high risk of the disease chickenpox in severe (eg, patients with leukemia or receiving treatment immunosuppressants). In cases where there is no way to prevent contact with the above mentioned persons, should weigh the potential risk of transmission of the vaccine virus and compare it with the risk of being infected, and transmit natural varicella virus.
Vaccinated patients who are identified lesions for 3 weeks after vaccination, should avoid any contact pregnant women (especially during the first trimester of pregnancy) and immunodeficiency.
Effects on ability to ability to concentrate
Product Form Lyophilisate: 0.5 ml (one dose) of clear, colorless glass bottle with capacity of 3 ml, a sealed rubber stopper and an aluminum cap with a break-pull-tab. Solvent: In 0.5 ml of transparent colorless glass ampoule of 1 ml capacity . at 0.5 mL syringe transparent colorless glass with a capacity of 1 ml or without needle. Needle cannula closed cap rubber. Cannula needleless syringe closed cap rubber. In one vial of vaccine and one vial with a solvent in the blister of high density polyethylene, in a cardboard box with instructions for use. In one vial of vaccine, one syringe with solvent 1 or 2 needles blister of high density polyethylene in a pack carton with instructions for use. in one vial of vaccine, one syringe without needle with a solvent in the blister of high density polyethylene, in a cardboard box with instructions for use. for 100 vials of vaccine into the package cardboard 10 instructions for use of solvent 25 in plastic vials blister, 4 in a separate blister cardboard pack.
Running low dose t3 clen cycle trying to lose bodyfat isn’t a real hot idea imo.